This episode talks a lot of things, but none of them are python... The Fermi paradox. Why NASA has been avoiding certain sites on Mars. The magical mix of oxygen and methane that Sagan thought might indicate life. Magnetic fields as necessary for life. Manufactured universes. It's definitely worth a listen, even if you don't use python.
Talk Python To Me: #276 Geekout: Life in the solar system and beyond https://talkpython.fm/episodes/download/276/geekout-life-in-the-solar-system-and-beyond.mp3
Just a general instance with a catchy name. We're running glitch-soc!